Tim, Joe, Stan and Bart are a group of four best friends. They call themselves "The Dregs" and organise "Weekends of Manliness" together, during which they undertake activities such as camping, drinking, gaming, and other "manly" activities. However, all of them, unbeknownst to each other, are harbouring a secret. They are all crossdressers. Fearful of being rejected by the other Dregs, they hide it as best they can. They are so far in the closet that they've broken through the drywall and have run off. But each member of The Dregs encounters a challenge that threatens to out them. To keep their shame hidden and hold on to their friends, they must face off against blackmailers, cops, murderers, duffle bags, conservatives, onions, drones, phallometers, psychologists, TERFs, conspiracies, the LGBTIQA+ community, mega corporations and, most concerning of all, their own desires.